EDUCATION AND PROFESSIONAL APPOINTMENTS
Christy (Smith) Holland attended Wellesley College where she majored in Physics and Music. Thereafter she completed an M.S., M.Phil. and Ph.D. at Yale University in Engineering and Applied Science. Dr. Holland is an Associate Professor in the Department of Biomedical Engineering (UCBME) in the Colleges of Medicine and Engineering. She coauthored a Whitaker Foundation Special Opportunities Award in 2000 that helped fund the creation of this interdisciplinary department, which first opened its doors on January 1, 2001. She is a fellow of both the Acoustical Society of America (ASA) and the American Institute of Ultrasound in Medicine (AIUM), for whom she has also served two terms as Secretary. She assumed the editorship of Ultrasound in Medicine and Biology, the official Journal of the World Federation of Ultrasound in Medicine and Biology, in July 2006. Dr. Holland is actively involved in teaching biomedical engineering and medical imaging in both the undergraduate and graduate curriculum of UCBME, during two of the three academic quarters. She serves as both a mentor and advisor to students within and outside of the UCBME educational programs. Dr. Holland has consulted in the field of architectural acoustics and continues to perform locally with the Knox Choir under the direction of Earl Rivers.
RESEARCH INTERESTS
Christy Holland's research interests include ultrasound-assisted thrombolysis for stroke therapy, ultrasound-mediated drug delivery, bioeffects of diagnostic and therapeutic ultrasound, and acoustic cavitation. She is the principal investigator of an NIH RO1 grant entitled, “Ultrasound-Assisted Thrombolysis for Stroke Therapy.” Successful completion of these studies will contribute significantly to her long-term goal to develop an ultrasound-assisted thrombolysis system that delivers and enhances thrombolytic therapy in the cerebral vasculature and rapidly restores perfusion after ischemic stroke. Dr. Holland is also principal investigator of two subcontracts to NIH RO1 grants entitled, “Targeted Liposomes for Acoustic Cardiovascular Imaging” and “Echogenic Targeted Liposomes for Transfection/Drug Delivery” in collaboration with investigators at the University of Texas Health Science Center in Houston, Texas. The goal of these projects is to develop echogenic liposomes to highlight and enhance vascular pathology, to determine, quantitate, and characterize the stage, extent, and pathophysiologic development of atherosclerosis. This research will aid in directing therapy to improve physiologic flow following clinical intervention. As a result of her research, Dr. Holland has gained wide recognition at UC, nationally and internationally for her excellence and contributions in ultrasound research.
PUBLICATIONS: SCOPUS
PUBMED
CONTACT
Department of Biomedical Engineering
University of Cincinnati
231 Albert Sabin Way, MSB, 6167
Cincinnati, Ohio, 45267-0586
Phone: (513) 558-5675
Email: christy.holland@uc.edu
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